In order to fully prepare for a large-scale emergency, you need to take the time now to establish a well thought-out plan.
Be sure you and your family have a back-up plan for taking care of sick children or other loved ones at home.  Below are some American Red Cross guidelines for creating your own family emergency plan. Commit a weekend every six months to update phone numbers and supplies, and to review your plan with your family.
For information from the American Red Cross on how to prepare your work place for an emergency: